Tuesday, 24 September 2013

Herpes virus cleared from blood for first time

A COMMON virus that can reduce lifespan and cause blindness has been cleared from human blood for the first time.
Cytomegalovirus (CMV), a type of herpes virus, is carried by about 70 per cent of people and, although it usually doesn't cause illness, shaves 3.7 years off life expectancy.
In people with a weakened immune system, however, the virus awakens and can cause serious illness and blindness. This can be a particular problem if the only available donor for a bone marrow transplant is infected with CMV and the recipient is not.
CMV only expresses a handful of genes when it is dormant. One of them is UL138. To investigate what it does to cells, Michael Weekes at the University of Cambridge and colleagues grew healthy human cells alongside cells that were made to express UL138 in the presence of labelled amino acids – the raw ingredients used to make proteins. They then used mass spectrometry to identify how UL138 changed the cells' expression of proteins.
"We know that viruses remodel the landscape at the surface of the cell, so we've been asking 'what proteins are on the cell surface and how does CMV change that?'" says Paul Lehner, also at Cambridge, who supervised the work. CMV appears to dampen the production of a protein called MRP1 that pumps toxic chemicals out of cells – including the cancer drug vincristine. If infected cells can no longer pump out vincristine, perhaps this would kill them while sparing healthy cells that remove the poison?
To find out, the team took blood samples from 15 volunteers with CMV, treated the samples with vincristine and then reactivated the virus. "We either dramatically reduced or eliminated our ability to [detect] any virus," says Lehner, who presented the results at the Strategies for Engineered Negligible Senescence conference in Cambridge this month.
"It will be fascinating to see how this new method comes to be applied in clinical practice," says Paul Moss of the University of Birmingham, UK. Vincristine can have severe side effects, so is unlikely to be used to clear CMV in healthy people or transplant patients. However, it could be used to treat donor blood or stem cells from bone marrow before transplantation.

Samsung Galaxy Tab 3 7.0 Review

Samsung Galaxy Tab 3 7.0 Review

review
Rating: Average
3/5 image description
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Features:
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Performance:
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Value:
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Design:

PROS

  • Good video playback capabilities
  • Many preloaded apps and services
  • Responsive touchscreen

CONS

  • Underwhelming performance
  • Plasticky build
  • Too big to be your primary phone
MRP: 17745

Summary

The upgrade in specifications on paper from the Tab 2 to the Tab 3 isn't spectacular. For the price you pay, you get a tablet that gets the job done, but feels lacking if you are a heavy user and want to play graphically heavy games and want a lot of multitasking. For heavy-duty use, you have devices such as the Nexus 7 (even better if you can get your hands on the second gen one from the US) as the tablet has a better display, better power under the hood and a stock Android interface. If you are in the market to pick up a sub-Rs. 20,000 tablet, you may want to consider options such as the Nexus 7, Asus Fonepad, Zync Quad 8 before making your purchase decision.
Samsung had a very successful product in the Galaxy Tab 2 P3100 last year. It had a 7-inch display, good power under the hood and also had the ability to make calls. It was surprising to see a large number of people carry the device with them and use it as their primary smartphone in spite of its large chassis, but at least some users had the sense to use it with a Bluetooth or wired headset. The Tab 2 was really good as it offered the best of both worlds- tablet and smartphone, to the consumer at a time when Android had taken over as the most popular OS in the world.



Fast-forward a year and we now have the Tab 3 in our hands. Is this the evolutionary next step for a successful tablet or will it crash and burn?

At a glance
Starting with the specifications, the Galaxy Tab 3 211 boasts of Wi-Fi and 3G connectivity. It has a 7-inch display with a 1024x600 pixel resolution and is powered by a dual-core 1.2GHz CPU coupled with 1GB of RAM. The device has 8GB built-in storage expandable up to 64GB via a microSD card. The rear of the tablet has a 3MP camera and the front has a 1.3MP camera for video chatting. The device is 9.9mm in thickness and weighs a mere 304 grams. A 4000mAh battery powers the entire package.

Here is a quick look to see where the Tab 3 stands against the competition, which includes the Asus Fonepad, the Galaxy Tab 2, Zync Quad 8 and the Nexus 7, in terms of specifications.


The Galaxy Tab 3 hasn’t broken any barriers with regards to specifications and we have tablets available in the market, such as the Asus Fonepad, that offer better specifications on paper.

Design
Staying true to the Samsung tradition, the Galaxy Tab 3 211 has the same look and feel as its predecessor, the Tab 2. The biggest difference is that it’s thinner, measuring 9.9mm in thickness. The tablet is relatively slim for its price point but it doesn’t hold the title for the slimmest tablet in the market (currently held by the Sony Xperia Tablet Z). On the face of the device you have the standard Samsung design – front facing camera and earpiece above the display and the home physical button along with the capacitive ‘menu’ and ‘back’ buttons on either side.

The ports and connectivity options are standard too. You have the microSD card slot and the SIM card slot on the left of the device secured under flaps. The right houses the power button along with the volume rocker and the top has the headphones jack. The bottom has the microUSB port for charging and data transfer. On either side of the microUSB port you have the speakers. The rear of the tablet houses the camera and there is no flash. The back of the tablet is traditional Samsung plastic and you don’t have access to the battery.


Samsung is going with the “if it ain't broke don’t fix it” philosophy with the design of the Tab 3 and if you are happy with a plasticky build then the design of the tablet may appeal to you. However, we have seen devices such as the Asus FonePad and the Zync Quad 8 boast of impressive design and build.

UI and Interface
Staying true to tradition you have the standard TouchWiz UI overlaying the Android OS on the Galaxy Tab 3. The tablet comes preloaded with a bunch of apps although the suite isn’t as large as what we have come to see from other Samsung devices. You do have access to the Samsung App store in addition to the Google Play store on the tablet though.

From the lock screen you have shortcut access to five apps – phone, messaging, browser, camera and Google Now. The tablet compromises on features such as Multi-Window apps, which are missed and Smart Stay which we aren’t. You can however watch videos in a smaller window while running other apps on the tablet.

We have seen the TouchWiz UI evolve quite a bit on the Note II, Note 800, Samsung Galaxy S4 and more and looking at a basic version of the UI on the Tab 3 feels like a step back.


Samsung has also introduced My Services with the Tab 3. My Services offers users services such as My Education, My Offers, My Games, My Music, My Movies and My Education.

My Education: This service gives you access to educational content ranging from pre-school, school, high school, and even content for competitive exams. Students will have access to 2000 e-books and 1000 learning videos for students. You can read a sample of the educational content or purchase it with the simple click of the button.

My Music and My Movies: You have access to a large library of movies and music to choose from. You can access this content with “coins”- each movie or song costs a certain number of coins. To put this in real world value, one coin is equal to one rupee. You can always download third party apps such as BigFlix and more to enjoy movies on the go.

My Offers: My Offers gives users access to deals and schemes available at stores listed near you. While using the app, we saw that there were a few deals available on electronic items available at a nearby Reliance Digital. The app features deals from 350+ brands and 25000+ merchants in India.

Performance:
Since the tablet is priced at Rs. 17,745, lets take a look and see how it compares to other devices in the same price range such as the first gen Nexus 7 and the Asus FonePad.




The scores of the Galaxy Tab 3 are slightly better than the Asus FonePad and lower than the first generation Nexus 7 (that has a quad-core processor).

Moving on to the day-to-day performance of the Tab 3,  we found that the tablet has a very responsive touchscreen. The interface is also smooth and responsive. Browsing the Internet, playing games, and generally anything to do with navigating the interface using the touchscreen is a good experience.

The keyboard on the device feels slightly cramped in landscape mode at first. Then you realize that there is spacing between the alphabets to make typing a lot more seamless and you will get used to the keyboard in no time.

The 7-inch display has a 1024x600 pixel resolution giving it 170ppi pixel density. The display has good viewing angles and as a stand alone device the display looks ok. It’s worth pointing out here though that there are 7-inch tablets available in the market that show off a 720p display. Keep the Tab 3 near one of these tablets and you will be able to make out the difference in the quality of the display. Even though the 1024x600 pixel resolution gets the job done, we wish the resolution was higher.


Speaking of games, all of them worked on the tablet. Graphically heavy games were met with some lag and there were some levels in Angry Birds Star Wars as well that stuttered when the action got too intense on screen.

To put things into perspective, the calling capabilities of the Tab 3 are as good as the Tab 2 if not better and that is a good thing seeing that the Tab 2 had a good speaker and earpiece sound quality while making calls.

The 3MP rear-facing camera gets the job done when the lighting conditions are very good. In broad daylight we got some good looking images. But once the lights go out, the quality of the camera drops radically.


Natively the Samsung Galaxy Tab 3 recognised all the video formats we threw at it – AVI, MP4 and MKV. The device was a treat to watch videos on. If you want, you can use the power button to lock the interface of the tablet while watching videos. This means that you can’t access the video’s timeline, adjust the volume or exit the video until you have unlocked the device. This is interesting as it gives you the ability to enjoy the movie and not get disturbed when you accidently press the home or back button.

In terms of its battery life, the Samsung Galaxy Tab 3 7.0 lasted for 6.5 hours in our continuous video playback test. In the test, we ran a 720p MP4 movie on loop with the brightness and volume set at maximum. The Wi-Fi of the tablet was on as well. This means that under regular conditions, the tablet should last you more than a day on a single charge.

Karbonn Smart A51 dual-SIM Android smartphone available online for Rs. 3,499

Karbonn Smart A51 dual-SIM Android smartphone available online for Rs. 3,499


24-09-2013
Karbonn has launched an entry level Smart A51, the device boasts of Android ICS, 1 GHz processor and dual sim for Rs 3,499 in India.
Karbonn Smart A51 dual-SIM Android smartphone available online for Rs. 3,499

Karbonn's latest smartphone, Smart A51, is now available on various e-retailers for Rs. 3,499 in India.
The Karbonn Smart A51 features a 3.5-inch HVGA capacitive TFT display with 480 × 320 pixels resolution. The handset is powered by a 1GHz single-core processor and runs on outdated Android 4.0 Ice Cream Sandwich OS. It has a 3.2MP rear camera with LED flash and video recording as well as a front facing VGA camera.
The Smart A51 has 256 MB of RAM, 512MB of internal storage and expandable storage up to 32GB via microSD card. The Android handset supports dual-SIM and supports connectivity options like EDGE, GPRS, Bluetooth, Wi-Fi and micro USB . The Karbonn Smart A51 comes with an 1100 mAh battery.
Other features included in the device are Gmail, GTalk, Google Play, Google Search, Karbonn Live, Android Browser, Outlook emails and is WAP enabled.
Karbonn had recently launched the Smart A1 Star and A5 Star budget devices under the 5K price segment. The devices have a 1GHz processor coupled with 256 MB of RAM and 512 MB of built-in storage expandable up to 32 GB via microSD card. The smartphone have a 3.2 MP rear camera and a VGA front-facing camera for video calling. Both the mobile phones offer connectivity options like Bluetooth, USB, GPRS, EDGE and has dual-SIM (GSM+GSM) capabilities. The Smart A1 and A5 are available for Rs. 3,514 and Rs. 4,890 respectively on various e-commerce sites.

New Smart NaMo Saffron Android smartphones available for pre-order on Snapdeal

New Smart NaMo Saffron Android smartphones available for pre-order on Snapdeal

The Smart NaMo Saffron One and Two Android phablets are now available for pre-booking on Snapdeal for Rs 999.
The Smart NaMo Saffron One & Two large screened smartphones manufactured by NaMo, an abbreviation for Next Generation Android Mobile Odyssey are now available on Snapdeal. The online retailer is offering pre-booking of the smartphones for Rs. 999 and the phones are expected to be released in the second week of October.
The Smart NaMo Saffron One has a 5-inch Full HD display with 1920 x 1080p resolution. The device runs on Android 4.2.1 and is powered by a quad core 1.5 GHz processor with 1GB and 2GB RAM depending on the variant. The Saffron One has a 13 MP auto focus rear camera with LED Flash and a 5 MP front-facing camera for video calling. The handset supports Dual SIM (3G + 3G) with Dual Standby, 3G, Wi-Fi 802.11 b/g/n, Bluetooth 4.0 and aGPS connectivity.
The Smart NaMo Saffron Two has a 6.5-inch Full HD display with 1920 x 1080 pixels resolution. The Saffron Two runs on runs on Android 4.2.1 and is powered by a quad core 1.5 GHz processor with 2GB RAM. It has a 13 MP auto focus rear camera with LED Flash with 1080p Full HD video recording and a 5 MP front-facing camera for video calling. It supports Dual SIM (3G + 3G) with Dual Standby, 3G, Bluetooth 4.0, Wi-Fi and aGPS.
The Smart NaMo Saffron One is available in white and black and is available in 16GB with 1GB RAM for Rs. 18,000 and 32GB with 2GB RAM for Rs. 23,000.The SmartNaMo Saffron Two is available in white featuring 32GB memory and is available for Rs. 24,000 in India.

BBM for Android episode: BlackBerry clarifies its side

BBM for Android episode: BlackBerry clarifies its side

on
25-09-2013
The update does not give any idea about when the BBM rollout for Android and iOS will start, but confirms that the older versions of the app that people downloaded on Android was the reason the rollout was stopped.
BBM for Android episode: BlackBerry clarifies its side
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Putting a rest to all speculation about why the BlackBerry Messenger for Android and iOS isn’t available at the moment, BlackBerry has released its side of the entire episode, where the company blames the leaked versions of BBM for causing the issue that “impacted the system in abnormal ways”. It was just yesterday that we were mentioning on this website regarding the serious need of ensuring some quality control on the Google Play Store. (Read it in detail here).
Andrew Bocking, head of BBM at BlackBerry clarified BlackBerry’s side in a post. He says, “Last week, an unreleased, older version of the BBM for Android app was posted on numerous file sharing sites. We were aware of an issue with this unreleased version of the BBM for Android app. This older version resulted in volumes of data traffic orders of magnitude higher than normal for each active user and impacted the system in abnormal ways. The version we were planning to release on Saturday addressed these issues, however we could not block users of the unreleased version if we went ahead with the launch. We attempted to address the problems caused by the unreleased version throughout the day on Saturday, but as active users of the unreleased app neared a million – and accelerated – it became clear that the only way to address the issue was to pause the rollout for both Android and iPhone.”
However, all is not lost, despite BlackBerry confirming that the BBM rollout will not happen this week at least. “The team is now focused on adjusting the system to completely block this unreleased version of the Android app when we go live with the official BBM for Android app. We are also making sure that the system is reinforced to handle this kind of scenario in the future. While this may sound like a simple task – it’s not. This will take some time and I do not anticipate launching this week.”
Clearly, because of the “open” nature of one platform, the iOS users also have to suffer, as BlackBerry is in the process of a massive cleanup at the system level. Maybe, too much freedom is a bad thing.

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